Diabetes Treatment May Lie In Helping Muscles To Burn Fat Better

“Scientists in Sydney and Melbourne have produced results that could silence the current debate about exactly how fat molecules clog up muscle cells, making them less responsive to insulin. The finding is an important milestone in understanding the mechanisms of obesity related insulin resistance, a precursor of Type 2 diabetes. Dr Clinton Bruce, first working with Professor Ted Kraegen from Sydney's Garvan Institute of Medical Research, and then with Professor Mark Febbraio from Melbourne's Baker IDI Heart and Diabetes Institute, has added to evidence that fat molecules clog up the cytosol, or cell interior, but not the mitochondrion, or energy powerhouse of the cell. This is an important distinction because the groups have also found a way to reduce the build-up of fat molecules in the cytosol by increasing the ability of mitochondria to take in fat molecules and burn them. The finding, already online and critical for our understanding of fat metabolism, will be published in a future issue of the prestigious international journal Diabetes.”

http://www.medicalnewstoday.com/articles/136908.php