Finds Fat Mass and Obesity Associated Genes Increase Risk of Disease In Mexican Americans

“A study from the University of Southern California (USC) suggests people of Mexican-American descent who have genetic variants of fat gene FTO and Arachidonate 5-Lipoxygenase (5-LO) had higher triglyceride and lower HDL levels. The findings were presented as an oral presentation on Sunday, June 8, at the American Diabetes Association 68th Scientific Sessions held in San Francisco. ‘Our results confirm the association between FTO and fat mass and indicate that the 5-LO promoter modifies the association between FTO and lipid levels,’ says Mary Helen Black, candidate for PhD in Statistical Genetics and Genetic Epidemiology, at the Keck School of Medicine of USC and lead author of the study. ‘The genetic interaction between 5-LO and FTO was significantly associated with an inverse relationship between triglycerides and HDL levels.’”

http://www.newswise.com/articles/view/541606/